Senior Finance Business Partner (Drug Design and Development), London, UK

About the role

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery. Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture. The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you. About Iso Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed. Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases. We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design. Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI. Your impact As our Senior Finance Business Partner (Drug Design and Development), you will serve as the dedicated partner to our drug discovery organisation for both strategic and operational finance. You will be a critical contributor to the success of this team and will be responsible for financial management of all drug development-related work from discovery to preclinical testing. This is a new role supporting our team based in London. You will have the opportunity to bring financial thought leadership and rigor to key stakeholders as Iso builds its drug portfolio and march towards its mission to Solve All Disease. About you - Collaborative Partner: Someone who builds trusting relationships across all levels, acts as a strategic thought partner and bridges between science and finance. - Proactive Problem Solver : A curious, resourceful mindset with the drive to resolve issues proactively and pragmatically, and to optimise our playbook and processes for future success. - Detail and Process Oriented : Highly organized and meticulous with budgets, forecasts, and reporting. Able to balance multiple workflows whilst maintaining high standards. - Independent and Growth-Oriented : A self-starter, always looking for ways to streamline processes and leverage technology (particularly AI) to increase efficiency. What you will do - Business & Financial Partnering: Serve as the primary finance partner for the Drug Design and Development team. Provide strategic thought partnership to support delivery of portfolio objectives. - Budgeting and forecasting: Lead end-to-end budgeting, forecasting, and resource planning. - Program and asset economics: - Provide financial decision support for the Portfolio Steering Team. Build project-level NPV and risk-adjusted valuation models for pipeline assets to support portfolio prioritization. - Partner with Business Development to model economics for biopharma partnerships and licensing deals, research collaborations and milestones. - Research Oversight & Advisory: Partner with our External Research team and Procurement during RFP processes to evaluate, benchmark, and negotiate budgets with vendors. - Reporting & Process Improvement: Deliver regular variance analysis and continuously enhance financial reporting and workflows to support portfolio growth. Oversee robust and efficient accruals processes. Skills and qualifications Essential: - Drug Development Finance Expertise: Direct experience managing R&D / drug development finance and FP&A/partnering within biotech, pharma, or life sciences. - Finance modeling: Deep experience building and maintaining robust financial models for portfolio prioritisation and project NPV. - Education & Analytical Skills: Degree in Finance, Accounting, Economics or other quantitative field. - Communication & Rigor: Clear executive-level communicator for both technical and non-technical audiences. Strong attention to detail and ability to manage competing priorities in a fast-paced environment. - Teamwork and collaboration: Proven track record in business partnering, influencing senior leadership, and excellence in stakeholder management. - AI to drive efficiency: Experience in utilizing LLMs and other AI to drive efficiency Nice to have: - Professional accounting qualification (e.g., ACA, ACCA, CIMA, CPA, or equivalent). - Life sciences background/experience highly desirable - Experience using Google Workspace (Sheets, Slides etc) . - Experience implementing or managing financial systems (e.g. ERP, procurement). Culture and values We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it. Thoughtful Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day. Brave Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less. Determined Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we. Together Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere. Creating an extraordinary company We believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact. We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know. Hybrid working It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call. Please note that when you submit an application, your data will be processed in line with our privacy policy . >> Click to view other open roles at Isomorphic Labs